2000 Vol. 24, No. 6

Display Method:
Current clinical PET status and it's most recent advances in the globe
WANG Shuxia, PEI Zhugou
2000, 24(6): 241-245.
Abstract:
As uninvasive functional imaging technique in vivo, PET was widely used in the field of clinical research and clinical application.Currently, PET was getting more and more attention all over the world.To locate the hot spots and most dynamic advances of PET, we retrieved all the material from internet and gave a global review.Focusing mainly on the clinical research and its application, such as neurology, psychiatry, oncology and cardiology.
PET/CT scanner-fusion of anatomic and functional images in a single device
ZHAO Jun
2000, 24(6): 246-249.
Abstract:
Recently, combined PET/CT is a new imaging system which enable acquire co-registered anatomic and biological function images in a single scanning session.PET/CT is valuable for improving tumor localization, planning of radiation therapy, defining biopsysite and evaluating response to therapy.CT can also provide low-noise CT-based attenuation correction for PET emission scan.The design and performance, clinical application, advantages and some technical limitation of a combined PET/CT scanner were summarized briefly in this paper.
The evaluation of 11C-flumazenil PET in the localisation of epileptic foci
HU Silong
2000, 24(6): 249-254.
Abstract:
the density of central benzodiazepine (cBZR) receptor is significanly reduced in epileptic foci and it is regdarded as the specific biochemical marker of epileptic foci.11C-flumazenil PET can measure the cBZR desity and is superior to MRI and 18F-FDG in accurate presurgical identification of epileptic foci.
Oncological applications of 18F-FDG PET imaging
LI Lin
2000, 24(6): 254-258.
Abstract:
Considering normal distribution of 18F-FDG in human body, 18F-FDG imaging using PET can be applied to brain tumors, colorectal cancer, lymphoma, melanoma, lung cancer and head and neck cancer.This article briefly focuses on application of 18F-FDG PET imaging to breast cancer, pancreatic cancer, hepatocellular carcinoma, musculoskeletal neoplasms, endocrine neoplasms, genitourinary neoplasms, esophageal and gastric carcinomas
The application value of 18-fluorine fluorodeoxyglucose positron emission tomographic imaging in the differential diagnosis of benign and malignant pancreatic tumor
GUAN Liang, LU Zhongwei
2000, 24(6): 259-263.
Abstract:
18-Fluorine-fluorodeoxyglucose PET imaging has a high sensitivity, specificity, positive predictive value and negative predictive value in the diagnosis and differeniation between panreatic benign and maignant pancreatic mass, and also has an important practical value for searching liver, lung and lumph node metastasis, confirming therapeuic protocol and fellow up studying after resection of malignant mass
Application of 18F-FDG PET scan in patients with differentiated thyroid cancer
KANG Yuguo
2000, 24(6): 264-267.
Abstract:
Poorly differentiated thyroid cancer lesions often lose the ability to concentrate radioactive [131I] iodine and exhibit increased metabolic activity, as evidenced by enhanced glucose uptake.18F-FDG PET was able to localize residual and metastatic thyroid cancer lesions in patients with negative diagnostic 131IWBS and elevated serum thyroglobulin levels, although it uas not sensitve enough to detect mivimal metastatic disea in cervical nodes.multivariate analysis demonstrated that the single strongest predictor of survial was the volume of FDG-avid disease.Subjects with a FDG volume greater than 125mL or with SUV greater than 10g/mL have significantly reduced short survival.
Toxicological issues after depleted uranium weapons attacked
ZHU Maoxaing
2000, 24(6): 272-275.
Abstract:
Depleted mallium (DU) is a byproduct of the uranium enrichment for producing nuclear reactor or nuclear weapon.DU is used in the military as an armor-piercing projectile due to its hardness, strength, and density.A lot of DU weapons were fired in the Gulf War, and bring about critical environmsntal and intemal contamination.Therefore, DU becomes suddenly a hot issue.In this paper, some toxicological problems after DU weapons attacked have been reviewed, which include features of iaternal DU contamination.hazard of wound contamination and inhalation with insoluble uranium, and other urgent toxicological issues.The healthy effects of implanted with depleted uranium pellets were illustrated in pahicular.
Stimulative effects of low dose radiation and their mechanism
LU Duicai
2000, 24(6): 275-281.
Abstract:
Studies related to stimulative effects of low dose radiation began in the late 1970 s.In recent years, these studies have focused on the mechanism of the stimulation through low-dose-radiation induced proteins and gene regulation.This review consists two parts: epidemiological studies and radiobiological studies of stimulative effects of low dose radiation and their mechanism.
Applications of single cell gel electrophoresis assay in radiation research
HONG Chengjiao, ZHANG Junning
2000, 24(6): 281-284.
Abstract:
The single cell gel electrophoresis (SCGE), also called comet assay, is a sensitive and rapid method forDN A damage detection in individual mammalian cell.Its use has increased significantly in the past few years.Applications in the field of radiation medicine are reviewed and possible future directions of the technique arebriefly explored.