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, Available online , doi: 10.3760/cma.j.cn121381-202308029-00399
[PDF 1229KB]
Abstract:
Lymphoma is a malignant tumor of the immune system originating from lymph nodes and lymphoid tissues. It is characterized by insidious onset and strong invasion, and is one of the tumors with the fastest growing incidence rate in China. At present, PET/CT has been an important imaging technique for the initial staging, re-staging, early treatment response, efficacy evaluation, prognosis prediction, and follow-up of malignant lymphoma. Due to the heterogeneity of lymphoma, such as different types of lymphoma in invasiveness, tissue origins, immune phenotypes, the stage of disease, and treatment response of different populations, non-18F-FDG PET imaging technologies are expected to show advantages over 18F-FDG PET/CT in the targeted diagnosis and treatment of some specific types of lymphoma. We focused on the research progress of non-18F-FDG PET molecular imaging in lymphoma, comparing the similarities and differences, advantages and disadvantages, application characteristics and development potentials between non-18F-FDG imaging agents and traditional imaging agent 18F-FDG, so as to provide new ideas and methods for the specific targeted diagnosis and treatment and personalized precision medicine of lymphoma.
Lymphoma is a malignant tumor of the immune system originating from lymph nodes and lymphoid tissues. It is characterized by insidious onset and strong invasion, and is one of the tumors with the fastest growing incidence rate in China. At present, PET/CT has been an important imaging technique for the initial staging, re-staging, early treatment response, efficacy evaluation, prognosis prediction, and follow-up of malignant lymphoma. Due to the heterogeneity of lymphoma, such as different types of lymphoma in invasiveness, tissue origins, immune phenotypes, the stage of disease, and treatment response of different populations, non-18F-FDG PET imaging technologies are expected to show advantages over 18F-FDG PET/CT in the targeted diagnosis and treatment of some specific types of lymphoma. We focused on the research progress of non-18F-FDG PET molecular imaging in lymphoma, comparing the similarities and differences, advantages and disadvantages, application characteristics and development potentials between non-18F-FDG imaging agents and traditional imaging agent 18F-FDG, so as to provide new ideas and methods for the specific targeted diagnosis and treatment and personalized precision medicine of lymphoma.
, Available online , doi: 10.3760/cma.j.cn121381-202306024-00398
Abstract:
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is an indolent tumor that most commonly occurs in the gastric mucosa. The authors presents a patient with gastric MALT lymphoma who underwent imaging with 18F-fluorodeoxyglucose(FDG) PET/CT and 68Ga-Pentixafor PET/CT. By analyzing and comparing clinical symptoms, conventional imaging findings, and 18F-FDG and 68Ga-Pentixafor PET/CT images, it deepens the understanding of gastric MALT lymphoma imaging with 68Ga-Pentixafor among clinical physicians.
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is an indolent tumor that most commonly occurs in the gastric mucosa. The authors presents a patient with gastric MALT lymphoma who underwent imaging with 18F-fluorodeoxyglucose(FDG) PET/CT and 68Ga-Pentixafor PET/CT. By analyzing and comparing clinical symptoms, conventional imaging findings, and 18F-FDG and 68Ga-Pentixafor PET/CT images, it deepens the understanding of gastric MALT lymphoma imaging with 68Ga-Pentixafor among clinical physicians.
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