FDG肿瘤显像相关分子机制研究进展

Progression of molecular mechanisms of tumor ¹⁸F-FDG PET imaging

摘要: ¹⁸F-FDG(¹⁸F-氟代脱氧葡萄糖)PET显像是依靠不同组织对¹⁸F-FDG的吸收差异来完成的,¹⁸F-FDG在肿瘤中的摄取增高与肿瘤的代谢及增殖情况、病理分级、分化程度、细胞的增生活性、倍增时间等生物学特性密切相关。进一步研究FDG吸收机制,将有助于对肿瘤的生物学特性更深一步的了解。

Abstract: ¹⁸F-FDG (¹⁸F-fluorodeoxyglucose) PET imaging depends on different uptake of ¹⁸F-FDG in different tissues.The uptake of ¹⁸F-FDG in tumor tissue correlates with tumor's biologic behavours, such as metabolism, proliferating, pathologic stage, differentiation, the proliferating acitivity of cells and double times. With more knowlegement of the mechanisms of ¹⁸F-FDG uptake, weU know more about tumour's biologic behavours.