杜海豪, 谭雄木, 程留慧, 王亚洲, 窦允龙, 王道清. CT引导下经皮穿刺活检对周围孤立性肺磨玻璃结节的诊断价值[J]. 国际放射医学核医学杂志, 2019, 43(1): 27-31. DOI: 10.3760/cma.j.issn.1673-4114.2019.01.006
引用本文: 杜海豪, 谭雄木, 程留慧, 王亚洲, 窦允龙, 王道清. CT引导下经皮穿刺活检对周围孤立性肺磨玻璃结节的诊断价值[J]. 国际放射医学核医学杂志, 2019, 43(1): 27-31. DOI: 10.3760/cma.j.issn.1673-4114.2019.01.006
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Haihao Du, Xiongmu Tan, Liuhui Cheng, Yazhou Wang, Yunlong Dou, Daoqing Wang. Diagnostic value of CT guided percutaneous biopsy for peripheral solitary pulmonary ground-glass nodules[J]. Int J Radiat Med Nucl Med, 2019, 43(1): 27-31. DOI: 10.3760/cma.j.issn.1673-4114.2019.01.006
Citation: Haihao Du, Xiongmu Tan, Liuhui Cheng, Yazhou Wang, Yunlong Dou, Daoqing Wang. Diagnostic value of CT guided percutaneous biopsy for peripheral solitary pulmonary ground-glass nodules[J]. Int J Radiat Med Nucl Med, 2019, 43(1): 27-31. DOI: 10.3760/cma.j.issn.1673-4114.2019.01.006
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CT引导下经皮穿刺活检对周围孤立性肺磨玻璃结节的诊断价值

Diagnostic value of CT guided percutaneous biopsy for peripheral solitary pulmonary ground-glass nodules

    摘要
  • 摘要:
    目的 探讨CT引导下经皮穿刺活检对周围孤立性肺磨玻璃结节（GGO）的诊断价值。
    方法 选取2017年1月至12月行CT检查的59例肺GGO患者，均接受CT引导下经皮穿刺活检，经手术、临床或随访结果证实。根据肺GGO轴位最大直径、实性成分所占比例、病变位置、距胸膜的距离、穿刺针-胸膜的角度、调针次数进行分组，采用单因素分析测定诊断的准确率、灵敏度、特异度及并发症的发生率。混合型GGO中实性成分≤50%和>50%之间的良恶性比较采用χ2检验。
    结果 CT引导下经皮穿刺活检对59例周围孤立性肺GGO患者诊断的准确率、灵敏度和特异度分别为89.8%（53/59）、84.2%（32/38）、100%（21/21），病理结果均证实为腺癌。根据方法中的不同分组，测定诊断的准确率较高且均≥80%，灵敏度均≥75%，特异度均为100%，但总体并发症的发生率较高。混合型GGO实性成分≤50%和>50%之间的良恶性比较，差异有统计学意义（χ2=6.13，P=0.01）。
    结论 CT引导下经皮穿刺活检对周围孤立性肺GGO具有较高的诊断价值，GGO中实性成分比例与其恶性程度有一定的相关性。

     

    Abstract:
    Objective To evaluate the value of CT-guided percutaneous biopsy for diagnosis of solitary ground glass nodules(GGO) around the lung.
    Methods Fifty-nine patients with solitary frosted glass nodules around the lungs who underwent CT examinations from January 2017 to December 2017 were enrolled in the study. All patients underwent CT-guided percutaneous biopsy, which was confirmed by surgery, clinical, or follow-up, in accordance with the maximum diameter of the lung GGO axial position, the proportion of solid components, the location of the lesion, the distance from the pleura, the angle of the needle-pleural, and the number of needle adjustments. Univariate analysis was used to determine the diagnostic accuracy, sensitivity, specificity, and incidence of complications. A chi-square test was used to compare the benign and malignant between solid components ≤50% and >50% in mixed GGO.
    Results The accuracy, sensitivity, and specificity of the diagnosis of 59 patients with solitary pulmonary GGO were 89.8%(53/59), 84.2%(32/38), and 100%(21/21), respectively, thereby confirming the disease as adenocarcinoma. According to different groups used in the method, the accuracy of the diagnosis is higher than 80%, the sensitivity is higher than 75%, and the specificity is 100%, but the incidence of overall complications is also higher. The difference between the mixed GGO solid components ≤50% and >50% was statistically significant ( χ2=6.13, P<0.05).
    Conclusions CT-guided percutaneous biopsy has high diagnostic value for isolated GGO. The proportion of solid components in GGO has a certain correlation with the degree of malignancy.

     

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