Abstract: Simulation skill is playing an increasingly important role in medical imaging research, four-dimensional non-uniform rational B-splines-based cardiac-torso(4D NCAT) phantom is new tool for meoical imaging res earch and when combined with accurate models for the imaging process a wealth of realistic imaging data from subjects of various anatomies. Can be provided 4D NCAT phantoms have bend widely used in medical research such as SPECT, PET, CT and so on. 4D NCAT phantoms have also been used in inverse planning system of intensity modulated radiation therapy.