实验性近视眼视网膜多巴胺神经系统研究进展
Study and development of retinal dopamine nervous system in experimental myopia
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摘要: 近视眼是一种最常见的屈光不正。动物实验模型主要包括形觉剥夺性近视和离焦性近视两种,应用的实验动物主要为鸡和哺乳类。视网膜多巴胺系统与视觉经验对出生后眼球生长发育的调控密切相关,而视网膜多巴胺转运体的变化可能更为直接地反映了突触间隙多巴胺的变化。Abstract: Myopia is the most familiar ametropia. Animal experimental models include form deprivation myopia and defocus myopia. Experimental animals we often use are chicken and mammals. The retinal dopamine system and vision expierence have close relations with the regulation of eyeball's growth after birth, while the change ofdopamine transporter may reflect the change ofdopamine in the synaptic cleft more directly.