持续低剂量率照射治疗前列腺癌的生物学效应

The biological effect of continuous low-dose rate irradiation for prostate cancer

  • 摘要: 持续低剂量率照射在前列腺癌的临床治疗方面已经积累了大量的经验。对持续低剂量率照射的生物学效应研究表现在以下几个方面:①反剂量率;②辐射敏感性;③凋亡和凋亡相关蛋白表达;④细胞周期及周期相关蛋白表达;⑤癌相关修复基因表达。

     

    Abstract: The clinic work of low-dose irradiation in the prostate cancer has already accumulated a large amont of experience. Studied on the biological effect of continuous low-dose rate was shown in the following several aspects:① the inverse dose rate effect; ② radio sensitivity; ③ apoptosis and relevant protein expression of apoptosis; ④ cell cycle and relevant protein expression of cell cycle; ⑤ repair gene cancer.

     

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