Abstract: Previous studies have shown that positron emission tomography (PET) can measure the biochemistry and physiologic function change in pituitary, including blood flow, perfusion, glucose metabolism, protein metabolism, receptor density. This article reviews recently research of PET imaging in pituitary adenomas. It re-flects the diagnosis, therapy management and prognosis of pituitary adenomas can be demonstrated by PET with different positron tracers. Therefore, PET imaging can lead to the improvement in research of pituitary adenomas and neurology.