Abstract: Objective To research the symptom of breast X-ray of chronic schizophrenia and the influence of its clinical features. Methods Take 50 patients who have been under treatment in our hospital for over 5 years as sample of psychotic group and same number of healthy people as control group. Analyze their X-ray films, using statistics to deal with their lung area of both before and after 5 years. Evaluation Criteria of X-ray:① Double layer rise;② Single or double lung base subsegmental atelectasis;③ Heart drown;④ Heart turing with the heart apex extending to the left;⑤The double lung bottom have gathering stripes;⑥The upper layer have wider shadow. Results The lung lobes of the patient group become smaller than they were 5 years ago. Data show great difference between two years(t=6.7099, P<0.01). The lung lobes of psychotic group become bigger than the control group in the first X-ray films (t=2.025, P<0.05), but smaller in the last X-ray films(t=5.512, P<0.01). Among them, 37 cases show double layer rise; 19 cases show single or double lung base subsegmental atelectasis; 24 cases show heart drown; 19 cases show heart turing and heart apex extending to the left; 37 cases show double lung bottom gathering stripes; 17 cases show wider shadow. Conclusion Morphology and pathology changes of schizophrenia patients are related to the side effect of anti-schizophrenia medicine and endocrine disorders.