Abstract: The value of ¹⁸F-FDG imaging with dual-head gamma camera has been demonstrated by a large number of clinical studies. For ¹⁸F-FDG coincidence imaging, however, effective factors are various from the patient's preparation to the results interpreted. The purpose of this paper was to outline the quality assurance procedures for this kind of imaging. Six items were included, such as acceptance testing and daily quality control of the imaging instruments, patients interviewing, ¹⁸F-FDG injection, data acquisition, data processing and results interpreter. After reading this paper, the readers should be awaked to the careful consideration of executing a coincidence imaging.