低剂量电离辐射效应

Adverse effects of low dose ionizing radiation

摘要: 在低剂量区域,电离辐射能够诱导一些大剂量实验中预测不到或传统放射生物学理论不能解释的效应,主要表现在三个方面①数cGy剂量诱导发生的适应性反应(adaptive rsponse,AR);②低剂量辐射超敏性(hyperradiosensitivity,HRS),其剂量通常为0.2~0.5Gy;③在临近的未受照细胞中诱导产生的旁效应(bystander effect, BE)。

Abstract: In low dose region, adverse effects could be induced by ionizing radiation. These effects are unpredictable from high-dose experiments or inexplicable with available radiobiological theories. There are mainly three aspects for these. First, adaptive response (AR)induced by several cGy irradiation. Second, low-dose hyperradiosensitivity (HRS). The dose is generally between 0.2-0.5Gy. Third, bystander effect (BE)induced in unirradiated neighboring cells.