Abstract: ¹⁸F-fluorodeoxyglucose PET is a very sensitive technology, yet it still has limitation such as low specificity. In this way, tracers used to study amino acid uptake, protein synthesis, DNA synthesis, cell proliferation, changes of other substrates of tricarboxylic aciol cycle metabolism, tumor hypoxia, immunological activity and receptor are expected to be new tumor imaging agent, The study and possible use of short half-life radiopharmaceuticals(excluding FDG) in oncology with positron emission tomography are reviewed in this article, those that include ¹⁸F and ¹¹C labeled compounds.