Abstract: Radionuclide imaging of pulmonary cancer develops very rapidly in recent years.Its important value on the diagnosis, staging, monitoring recur and metastasis after treatment, and judging the curative effect and prognosis has been demonstrated.Clinicians pay more attention to it than before.This present article introduces the imaging principle, clinical use, good and bad points, progress situation of ⁶⁷Ga, ²⁰¹Tl, ⁹⁹Tc^m, ¹⁸F and their labelled compounds, which are more commonly used in clinical.And introduces the clinical progress of radionuclide imaging of pulmonary neoplasm concerning ⁹⁹Tc^m-sestamibi (⁹⁹Tc^m-MIBI),⁹⁹Tc^m-HL91and ¹⁸F-fluorodeoxyglucose (ISF-FDG) with emphasis.