Abstract: With the evolution of imaging technology in the past two decades, currently anatomic targets including the trigeminal nerve (for trigeminal neuralgia), the thalamus (for tremor or pain), the cingulate gyrus, anterior internal capsule or amygdala (for pain or psychiatric illness), the globus pallidus (for symptoms of Parkinson's disease), and the hippocampus (for epilepsy) can be precisely located with computerized tomography, magnetic resonance image, single photon emission computerized tomography and positron emmission tomography;stereotactic radiosurgery gradually tends to perfection.Gamma knife therapy for nervous functional disorders has become the focus of interest in clinical study.