Abstract: Prostate cancer is a common malignant tumor in elder male.But it is difficult to visualize using conventional techniques. ¹¹C-choline is one of newly developed positron tumor imaging agent, which is being used in the imaging of prostate cancer recently because of its metabolism characteristic. We reviewed the use of it in diagnosis of prostate cancer by comparing with ¹⁸F-fluorodeoxyglucose, ¹¹C-acetate, ¹¹C-methionine.