腺苷试验与运动试验201Tl心肌灌注显像对冠心病诊断价值的比较

Comparison of adenosine stress and exercise stress 201Tl myocardial perfusion imaging for diagnosis of coronary heart disease

    摘要
  • 摘要: 目的 比较腺苷试验与运动试验201Tl心肌灌注显像对冠心病的诊断价值。方法 将41例临床疑诊冠心病患者随机分为两组,一组进行腺苷试验201Tl心肌灌注显像,一组进行运动试验201Tl心肌灌注显像。两组试验对象均同期(2周内)行冠状动脉造影术。以冠状动脉狭窄≥50%作为冠心病诊断的"金标准",比较两种负荷方法对冠心病的诊断价值。结果 腺苷试验201Tl心肌灌注显像对冠心病诊断的灵敏度、特异度、阳性预测率、阴性预测率、准确率分别为92.86%、57.14%、81.25%、80.0%、80.95%,运动试验201Tl心肌灌注显像分别为100%、60.0%、71.43%、100%、80.0%,两种负荷方法对病变冠状动脉的检出率分别为66.67%和72.22%。结论 两种负荷方法诊断冠心病的总体效能无显著差异。

     

    Abstract: Objective The aim of this study was to compare the diagnostic values of adenosine and exercise stress 201Tl myocardial perfusion imaging for detecting coronary heart disease (CHD). Methods 41 patients with suspected CHD were randomly divided into two groups. In one group adenosine stress was submitted, the exercise stress myocardial SPECT was performed in another. Coronary angiography (CAG) was performed in each patient within 2 weeks before or after SPECT. The result of CAG was taken as "gold standard" of CHD. They compared the diagnostic value of two methods. Results In adenosine group, the sensitivity, specificity, positive predictive value, negative predictive value, accuracy are 92.86%, 57.14%, 81.25%, 80.00%, 80.95% respectively. In exercise stress group, are 100%, 60.0%, 71.43%, 100%, 80.00% respectively. Detection rates of coronary artery lesions were 66.67% and 72.22% in two groups respectively. Conclusion Adenosine stress testing and exercise stress testing 201Tl myocardial perfusion imaging may provide similar value for detection of CHD.

     

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