Abstract: Human gliomas are one of the most aggressive tumors in brain which grow infiltrativly.Surgery is the mainstay of treatment.But as the tumor could not be entirely cut off, it is easy to relapse.Radiotherapy plays an important role for patients with gliomas after surgery.The efficacy of radiotherapy is associated with radio sensitivity of human gliomas.This paper makes a summary of curent situation and progress for radiosensitive genes of human brain gliomas.