腔内近距离放射治疗食管癌的特点和作用
The characteristics and effects in the treatment of esophageal cancer with intraluminal brachytherapy
-
摘要: 食管癌腔内近距离放疗是将放射源置于食管腔内进行放射治疗的一种方法,它可以作为表浅性食管癌或复发性食管癌的主要治疗手段,但更多的是将其作为局限性中晚期食管癌外照射后追加剂量照射的方法,这样可以提高肿瘤控制率和患者的生存率,对病变长度小于5cm或肿瘤局限于肌层的患者疗效更为明显。只要降低单次剂量、控制总剂量,腔内近距离放疗的早期反应可以耐受,后期并发症也可以得到控制。Abstract: Intraluminal Brachytherapy(ILBT) is one method of radiotherapy by delivering the radiation resource into the Intralumen of esophagus. ILBT has been proposed as the effective method in the treatment for superficial cancer of the esophagus. More frequently, it has been utilized as a boost after external beam radiotherapy (EBRT) in inoperable patients with localized esophageal carcinoma. ILBT with EBRT may improve local control and survival. The effect were found to be strongly correlated with tumor less than 5 cm in length or tumor confined to esophageal wall. The patients may tolerate in acute effects, and late complications may be controlled with lower single dose and reasonable total dose.