Abstract: Gated myocardial perfusion SPECT is a technique for the combined evaluation of myocardial perfusion and left ventricular function with in a single study. It is currently one of the most commonly performed cardiology procedures in a nuclear medicine department. Automation of the image processing and quantification has made this technique highly reproducible and practical in the clinical setting. In patients with coronary heart disease, gated myocardial perfusion SPECT enhances the diagnostic and prognostic capability of myocardial perfusionimaging, provides incremental information. It has shown potentials for myocardial viability, risk stratification, therapy and prognosis.