Abstract: Radiation-induced brain injury is awell-described complication of brain and neck cancers radiotherapy.With the increasing use of radiotherapy for brain and neck cancers in recent years,the incidence of radiation-induced brain injury which has influenced the sufferer's living quality and existence period seriously has markedly increased.As a result,the research to the radiation-induced brain injury seems to be more urgently.The article reviewed the mechanism and treatment and wanted to provide areference for the treatment which reduces incidence of radiation-induced brain injury.