Abstract: Objective To investigate the characteristics and regularity of skeletal metastases with gastric cancer of different pathological types and clinical stage. Methods Radionuclide bone imaging was analysed retrospectively in 132 cases of gastric cancer. And discussing in different pathological types, clinical stage, the number of bone metastasis and distribute sites. Results Total skeletal metastatic rate of gastric cancer was 15.9%(21/132). Multiple bone metastasis 90.5%(19/21). The ratio of bone metastasis of Ⅲ, Ⅳ stage is 18.4%, 26.6% respectively. Low deferential and undifferentiated adenocarcinoma is 15.2%, 20% respectively. Spine bones were the frequently involved metastatic sites, Thoracic and pelvis were the next. Conclusions Keletal metastases with gastric cancer is not frequet. Metastatic sites is widespread and late stage. Radionuclide bone imaging of regularly is useful for diaguosising, treating gastric cancer.