Abstract:
Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when boron-10 is irradiated with low-energy thermal neutrons to yield alpha particles and recoiling lithium-7 nuclei which have high energy and shortrange. BNCT is a binary approach:a boron-labeled compound is administered that delivered high concentration of
10B of the target tumor relative to the surrounding tissues. The therapeutic efficiency of BNCT is depended upon RBE and LET of the reaction and particles and the boron selectivity to cancerous cells. The development of BNCT, characteristic of radiation fields and calculations of energy deposition are described in this paper.