Abstract: ¹⁸F-fluorodeoxyglueose (¹⁸F-FDG) is the most widely used PET agent for imaging tumors. However, ¹⁸F-FDG PET showed a relatively high false positive rate when it is used to differentia the malignant and benign lesions. ¹¹C-aeetate metabolie PET may overcome some limitations of ¹⁸F-FDG PET and has elinieal potentials. It has demonstrated advantages over ¹⁸F-FDG PET in the tumors such as prostate cancer, hepatocellular carcinoma. Because of the metabolie characteristics of ¹¹C-acetate, it may be used to assess myoeardial viability, blood flow and peffusion.