18F-FDG PET显像在肿瘤学中的应用
Oncological applications of 18F-FDG PET imaging
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摘要: 从(氟代脱氧葡萄糖)在正常人体内的分布角度考虑,使用PET进行18F-FDG显像可应用于脑肿瘤、结直肠癌、淋巴瘤、黑色素瘤、肺癌以及头颈部肿瘤等。美国核医学会(SNM)已报道18F-FDG显像在原发性脑肿瘤、乳腺癌、骨肿瘤、肺癌、前列腺癌、黑色素瘤及淋巴瘤等中的应用。初步结果表明,葡萄糖代谢在坏死型及持续型生长肿瘤中有明显差别,当肿瘤局部FDG利用减低,提示治疗后有明显效果。本文简要综述18F-FDG PET显像在乳腺癌、胰腺癌、肝细胞癌、肌肉骨骼肿瘤、内分泌肿瘤、生殖泌尿道肿瘤和胃食道肿瘤中的应用。Abstract: Considering normal distribution of 18F-FDG in human body, 18F-FDG imaging using PET can be applied to brain tumors, colorectal cancer, lymphoma, melanoma, lung cancer and head and neck cancer.This article briefly focuses on application of 18F-FDG PET imaging to breast cancer, pancreatic cancer, hepatocellular carcinoma, musculoskeletal neoplasms, endocrine neoplasms, genitourinary neoplasms, esophageal and gastric carcinomas
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