Abstract: N-acetylglueosaminyl transferase(GnT) is related to the development of tumor and the cancer patients' prognosis by effecting the change of glucose's chain. Study on the transform of glycosyhransferase is benefit to the comprehension of the mechanism of biological behavior. The noninvasive diagnostic and treating methods of tumor will be provided along with the development of new imaging agent of tumor glucose analogue and its mechanism defined clearly.