18F-氟脱氧葡萄糖PET在恶性淋巴瘤中的应用

The role of 18F-fluorodeoxyglucoxe PET in malignant lymphomas

  • 摘要: CT是诊断恶性淋巴瘤常规影像学手段,核医学显像也是非常重要的检查方法,如67Ga显像。18F-氟脱氧葡萄糖(18F-FDG)PET以其在淋巴瘤中应用的显著优势逐步替代了67Ga显像。18F-FDG PET在淋巴瘤的早期诊断、准确分期、疗效的评价、复发和预后的估计等方面显示出了非常 重要的价值。随着PET-CT的广泛应用使得敏感性和特异性都有了进一步的提高。主要综述了18F-FDG PET在淋巴瘤诊断、分期、疗效评价中的应用。

     

    Abstract: The conventional imaging procedure is CT in diagnosis of malignant lymphomas. However, nuclear medicine imaging has also had a prominent role. Single-photon imaging with 67Ga-citrate(67Ga) has been widely used for lymphomas. Positron emission tomography(PET) with, 18F-fluorodeoxyglucose(18F-FDG) has gained a role in the staging and follow-up of lymphomas, largely replacing 67Ga as the nuclear medicine study of choice, 18F-FDG PET has proved useful in the staging, restaging, monitoring response of therapy and follow-up of Hodgkin disease and non-Hodgkin lymphoma. And the widespread use of PET-CT has also increased the sensitivity and specificity, reviewed the role of 18F-FDG PET in the management of patients with lymphoma.

     

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