Abstract: Diuresis renography is one of the classic methods for diagnosing upper urinary tract obstruction in both children and adults. However, in clinical practice, the results of diuresis renography were often influenced by many factors including diuretics, timing of diuretics injection, the slatus of renal function and hydration, the volume and compliance of collecting system, bladder fullness and so on. It is important to consider all the factors affecting diuresis renography during performing and interpreting diuresis renography.