半侧空间忽略定位研究

Study of localization of hemispatial neglect

  • 摘要: 半侧空间忽略(HSN)与脑卒中的愈后密切相关。大多数学者认为,HSN是由于介导方向性注意的网络结构损伤所致,包括额叶、顶叶和扣带回皮质及与之相连的皮质下区域丘脑、基底节和上丘。与忽略最相关的部位一般认为是右侧顶下小叶。人类颞-顶-枕连接区(temporal-parietal-occipital junction),即TPO连接区病变易致HSN。利用敏感的SPECT技术检测忽略患者脑损伤部位的局部脑血流(rCBF),进行定位及定量研究,可望为HSN的研究开辟新的天地。

     

    Abstract: Hemispatial neglect(HSN) is an important predictor of poor outcome after stroke. It is hypothesized to result from the damage to a network for directed attention which involves the frontal, parietal and cingulate cortices, basal ganglia, thalamus and superior colliculus. Neglect is most commonly associated with lesions in the right inferior parietal lobe. The damage of temporal-parietal-occipital junction causes HSN easily in human. The measurement of rCBF of lesions, and further to be oriented and quantified, can make a new view for HSN by use of the sensitive SPECT technique.

     

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