放射性标记的维生素B12及其衍生物在肿瘤诊治中的应用进展
Development of radiolabelled vitamin B12 and derivatives on oncology and tumor therapy
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摘要: 综述了基于维生素B12及其衍生物的放射性标记化合物的研究与临床试验情况,并着重介绍维生素B12的生物活性和放射性核素111In,10B,99Tcm(Re)标记的衍生物及其在肿瘤诊治方面的应用。Abstract: Current study and clinical application of the radiolabelled Vitamin B12 and derivatives are summarized. The biological activity of Vitamin B12 and the application of 111In,10B,99Tcm (Re)labelling derivatives on oncology and tumor therapy are mainly reviewed.