Abstract: Radioimmunoimaging (RII) used radiolabeled antibodies for diagnostic imaging of neoplasms.It is based on the Specific binding of antibodies and tumor antigen.Genetic engineering technology promoted the development of a variety of antibodies and derivatives as well as stimulated a indepth study of radioimmunoimaging.RII plays certain role in tumor diagnosis.Pancreatic cancer high degree of malignan, which arises hiding and progress rapidly.The treatment is difficulty.With development and improvement of monoelonal antibody and application of pre-localization technology and radioimmunoguided surgery, pancreatic cancer RII expected to become an important diagnostic method of the pancreatic cancer.