18F-FDG代谢显像标准摄取值的影响因素

Affect factors of the standardized uptake value for metabolic imaging with 18F-fluorine-2-deoxy-D-glucose

  • 摘要: 18F-FDG(18F-氟代脱氧葡萄糖)代谢显像在肿瘤、心肌存活及某些中枢神经系统疾病的研究、诊断中有着独特的临床应用价值,18F-FDG SUV(标准化摄取值)既能间接反映组织葡萄糖代谢率,又是一种简便快捷的临床常用影像半定量分析方法,但其影响因素众多,其中包括患者的身高、体重、血糖及胰岛素水平、显像时间以及感兴趣区的设置等,因此,临床应用过程中应注意对SUV测定的标准化。

     

    Abstract: Metabolic imaging with 18F-fluorine-2-deoxy-D-gluc (18F-FDG) has unique clinical application value in the investigation and diagnosis for clinical oncology、myocardial viability and some central nervous system disorders. The standardized uptake value is regularly used as analyzing way of demi-quantuative. It reflects indirectly constitution glucose metabolic rate, and it is also convenient and quick.But, because it may be affected by many factors such as body height, body weight, blood sugar and insulin level, and the image time after injection FDG, layout to regional of interest et al, it is very important that the standardized to SUV assay be payed attention in the process of clinical application.

     

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