Abstract: Radiation injury of blood vessels has become one of most important research field with the development of stereotactic conformal radiotherapy technique. But there were not adequate research in this field. In this article, the acute lesions and delayed lesions of radiation injury, coronary artery disease of radiation, and experimental radiation-induced vascular disease were discussed. Clarifying the research status, definitude the research direction, and assisting the clinic at a certain extent were the aim of this article.