99TcmO4-与99Tcm-HL91联合显像对甲状腺结节的诊断价值

Diagnosis of thyroid carcinoma using 99TcmO4-/99Tcm-HL91 imaging

    摘要
  • 摘要: 目的 用99Tcm-高锝酸钠(99TcmO4-)与99TcmO4-,9-二氮-3,3,10,10-四甲基十二烷-2,11-二酮(99Tcm-HL91)联合显像鉴别甲状腺结节的性质,评价其临床价值。方法 对65例甲状腺结节患者行99TcmO4-动、静态双时相显像,48 h后再对其进行呵99TcmO4-静态显像。显像结果示为冷结节的46例患者再行99Tcm-HL91乏氧显像,最后将两种显像结果与病理活检结果进行对比分析。结果 99TcmO4-显像对甲状腺结节诊断的灵敏度、特异度和准确度分别为78.6%、71.9%、73.9%; 99Tcm-HL91显像为88.7%、92.3%、91.4%,两者联合显像对甲状腺结节的诊断灵敏度为92.9%、特异度为93.8%、准确度为93.5%。结论 99TcmO4-与99Tcm-HL91两种显像方法相结合有助于提高诊断符合率。

     

    Abstract: Objective To evaluate the clinical value of 99Tcm-sodium pertechnetate(99TcmO4-)and 99Tcm-4,9-diaza-3,3,10,10-tetramethylododecan-2,11-dione dioxime(99Tcm-HL91)imaging in differentiation of thyroid nodules.Methods 99TcmO4- dynamic and static imagings were performed to the 65 cases of patients with thyroid nodules.After 48 hours,the 46 cases of patients whose 99TcmO4- static imaging prompt cold nodules underwent 99Tcm-HL91 hypexia imaging.And finally,compare the results of the two types imaging with biopsy results.Results The sensitivity,specificity and accuracy of 99TcmO4- imaging in the diagnosis of thyroid nodules were 78.6%,71.9% and 73.9% respectively.The sensitivity,specificity and accuracy of 99Tcm-HL91 imaging in the diagnosis of thyroid nodules were 88.7%,92.3% and 91.4%respectively.And the sensitivity,specificity and accuracy of Combining 99TcmO4/99Tcm-HL91 imaging were92.9%,93.8% and 93.5% respectively.Conclusion Combining 99TcmO4- and 99Tcm-HL91 imaging methods can improve the coincidence.

     

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