Abstract: The hippocampus is an important brain region related to learning and memory. MRI, PET and other imaging methods can provide structural, functional and glucose metabolism indicators of the hippocampus, and provide more imaging support for early screening and diagnosis of mild cognitive impairment (MCI). This paper mainly reviews the imaging research progress of hippocampal volume, hippocampal functional connectivity and hippocampal glucose metabolism in patients with amnestic MCI, with a view to finding more sensitive imaging indicators for the diagnosis of MCI.