Abstract: Pheochromocytoma(PCC) is a rare neuroendocrine tumor(NET), and accurate diagnosis is the key to treatment. At present, including radioactive iodine markers of iodine benzyl(MIBG) guanidine scanning, positron emission tomography(PET), radioactive nuclide labeled somatostatin analogue nuclear medicine functions such as scanning imaging in the diagnosis of pheochromocytoma have higher value. At the same time, the radionuclide therapy mediated by iodide and peptide receptor also has certain value in the palliative treatment of pheochromocytoma. The application of radionuclides in the diagnosis and treatment of pheochromocytoma was reviewed in order to provide help for the development of individualized treatment.