Abstract: Malignant melanoma is prone to metastasis and recurrence. It has become one of the seriously health-threatening malignant tumors. Early diagnosis and accurate staging are very important for prognosis and long-term survival. ¹⁸F-FDG PET/CT is a novel imaging technique that combines the functional data of PET with the morphological information of CT. It has been widely used in the diagnosis and staging, local recurrence, and therapeutic response evaluation of malignant tumour including melanonma. With the successful clinical application of integrated-PET/MR imaging system, It has taken a great step forward in multi-modal imaging technology field, thereby realizing synchronous data acquisition. To understand new progress of multimodal imaging technology in malignant melanoma, this article provides a review of the value of ¹⁸F-FDG PET/CT and PET/MR in the staging, local recurrence, chemotherapy response evaluation of melanoma.