Abstract: Alzheimer's disease (AD) is the main type of senile dementia and accounts for about 60% to 80% of dementia cases. With the prolongation of the average life expectancy of our country's population and the increase of the elderly population, the continuous increase of the incidence rate of AD brings a huge economic burden to the society and the family, which has attracted the attention of scholars at home and abroad. PET is an advanced clinical imaging examination technique that can provide a higher sensitivity and accuracy for the diagnosis of AD. In this paper, the application progress of PET imaging in Alzheimer's disease was reviewed.