99Tcm-MDP SPECT/CT融合骨显像评价骨折远期愈合能力的应用价值

Evaluation of fracture healing by 99Tcm-MDP SPECT/CT

  • 摘要:
    目的探讨99Tcm-MDP SPECT/CT融合骨显像技术评价骨折远期愈合能力的应用价值。
    方法回顾性分析2008年1月至2017年8月在我院治疗至少超过6个月的76例骨折患者的影像资料,其中58例经手术治疗,18例采用非手术方法治疗,所有骨折患者均未达到临床愈合标准。对76例骨折患者行SPECT显像、CT扫描和SPECT/CT融合骨显像,分析骨折端的放射性分布及CT特征,观察骨折端放射性浓聚是否连续性通过骨折线,跨越两侧骨折端,评价骨折远期愈合能力,最终骨折愈合情况经临床随访或手术证实。
    结果76例骨折患者,58例SPECT/CT融合骨显像显示放射性浓聚连续性通过骨折线并跨越两侧骨折端,诊断为骨折具有远期愈合能力,经对症保守治疗,证实52例骨折远期愈合,6例未愈合,SPECT/CT对骨折远期愈合诊断的准确率达89.66%(52/58)。18例骨折端未见明显连续性通过骨折线的放射性浓聚,诊断为骨折不愈合,且不具备远期愈合能力,均进行了手术治疗并证实为骨折不愈合,SPECT/CT对骨折远期不愈合诊断的准确率达100%(18/18)。
    结论SPECT/CT融合骨显像可较准确地评价骨折的远期愈合能力,具有重要的临床应用价值。

     

    Abstract:
    ObjectiveTo explore the application value of SPECT/CT on fracture healing.
    MethodsA retrospective analysis was done among 76 patients with fracture as evidenced by image data from January 2008 to August 2017. Fifty-eight cases with fracture revealed by a SPECT/CT fusion image with surgical treatment, 18 cases with nonsurgical treatment, and 76 cases of bone fracture clinical healing that failed to meet standards were retrospectively analyzed after more than 6 months of treatment. A SPECT/CT image fusion imaging device was applied to 76 cases of fracture detected with SPECT, CT scan, and SPECT/CT fusion imaging. The characteristics of the fractures in terms of radioactive distribution and CT were examined, and the radioactive strength of the fracture was observed to determine whether radioactivity passed continuously through the fracture line or crossed both sides of the fracture. The healing ability of the fracture was evaluated, and fracture healing cases were confirmed through surgery or clinical follow-up.
    ResultsA total of 76 fractures were collected and examined through SPECT/CT, and 58 cases of uptake that passed through the fracture line and crossed on both sides of the fracture end were obtained. This finding indicated that the fracture was in the process of healing and that fracture could heal. Furthermore, 52 cases were confirmed after conservative treatment was administered, and 6 cases of fracture were nonunion. For 18 cases, no nuclide concentration was detected in the fracture end, and the fracture was nonunion. The final diagnosis was confirmed through surgery, and the diagnostic accuracy rates were 89.66%(52/58) for fracture healing and 100%(18/18) for nonunion.
    ConclusionSPECT/CT imaging could accurately evaluate fracture healing and had an important application value.

     

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