Abstract: Ischemic heart disease has become a high incidence disease threating to human health, the judgement of the status about myocardial perfusion and whether the coronary is stenosis has great significance for preventing and treating ischemic heart disease. Dual-energy computed tomography myocardial perfusion imaging is always using for static evaluating myocardial blood pool imaging, diagnosing coronary artery disease and myocardial infarction in clinical medicine. The authors review the progress of dual-energy myocardial perfusion imaging via dual source CT in imaging principle, scanning methods, image acquisition and clinical applications.