Abstract: With the improvement of positron emission computed tomography (PET/CT) devices and the availability of cardiac positron tracers, the clinical interest in myocardial perfusion PET(PET-MPI) has increased over the years. PET-MPI enables noninvasive and accurate quantification of myocardial blood flow(MBF) and myocardial flow reserve(MFR), making it possible to enhance detection of early stages of vascular dysfunction, improve risk stratification of coronary heart disease, guide clinical management, evaluate efficacy and prognosis. The aim of this narrative review was to summarize the progress of cardiac PET for myocardial perfusion and its quantitative analysis.