Abstract: Hepatic fibrosis is a pathological process associated with chronic liver diseases, with significant morbidity and mortality.The current gold standard for the diagnosis of liver fibrosis is liver biopsy, but liver biopsy has many limitations.Currently, there is no noninvasive means of effective diagnosis of liver fibrosis.In the early stages of the disease, it can be reversed by active therapy.Thus, diagnosis and precise stages of liver fibrosis are important in controlling progression of the disease.Because of its noninvasive, high specificity and other advantages, molecular imaging has great potential use in liver fibrosis.This paper provides an overview of the latest advances in the diagnosis and stages of liver fibrosis using magnetic resonance imaging and nuclear medicine imaging.