Abstract: Prostate cancer has a high bone metastasis tendency. At the time of initial diagnosis, there is a high rate of bone metastasis. Early detection of bone metastases in patients with prostate cancer has important significance for staging, treatment and prognosis of prostate cancer. Radionuclide bone imaging(SPECT) is a commonly used imaging examination method of bone metastases, which had a higher detection rate in early bone metastases. Combined with X-ray, CT, MRI and other ways can improve the accuracy of bone metastases. This review summarizes the research status of the imaging examination of bone metastasis of prostate cancer, which provides the imaging evidence for early diagnosis of bone metastases.