分化型甲状腺癌骨转移诊断及疗效评价的核素显像研究进展

Diagnosis and evaluation of curative effect progress of radionuclide imaging methods in differentiated thyroid cancer of bone metastases

摘要: 分化型甲状腺癌（DTC）骨转移的诊断及疗效评价的核素显像方法较多，放射性核素显像在恶性肿瘤骨转移中的临床应用比较广泛，在DTC骨转移中主要用于骨转移的诊断、术后随访及疗效评价。放射性核素显像目前主要包括SPECT显像和PET显像，前者包括¹³¹I显像、⁹⁹Tc^m-MDP显像等，后者包括¹²⁴I显像、¹⁸F-FDG显像、¹⁸F-NaF显像等。笔者将放射性核素显像方法在DTC骨转移中的诊断及治疗进展进行综述。

Abstract: There are various radionuclide imaging modalities for the diagnosis and evaluation of curative effect about differentiated thyroid cancer with bone metastases. Radionuclide imaging is widely used in many kinds of malignant tumors with bone metastases. Recently, SPECT and PET are main included in the radionuclide imaging.The former main contains ¹³¹I、⁹⁹Tc^m-MDP imaging and the later one main contains ¹²⁴I、¹⁸F-FDG as wall as ¹⁸F-NaF imaging. This review concentrates on the commonly used radionuclide imaging methods in patients with DTC of bone metastases.