放射性心脏损伤诊断和防治的临床研究进展

Clinical research progress in diagnosis, prevention and treatment of radiation-induced heart disease

  • 摘要: 随着放疗在胸部肿瘤治疗中的广泛应用,其已成为胸部肿瘤患者必要且有效的治疗手段之一。在放疗中心脏不可避免地受到X线照射,从而引起心脏结构和功能的损伤性改变,即放射性心脏损伤(RIHD)。随着放疗技术的发展与进步,肿瘤患者的生存期明显延长,RIHD的发病率随之明显升高,尤其是迟发性RIHD,其发病率超过50%。遗憾的是,目前临床上针对RIHD的防治尚无有效的手段。因此,早期诊断、及早干预,对提高患者疗效及生活质量至关重要。笔者就RIHD的诊断及防治做一综述。

     

    Abstract: Radiation therapy is one of the necessary and effective treatment methods for the patients with thoracic tumors. However, the heart will be inevitably affected by irradiation simultaneously, leading to radiation-induced heart disease(RIHD). As the radiotherapy technology improving, the survival period is significantly prolonged in patients with tumor, the RIHD incidence increase as well, especially the delayed heart damage, reaching 50% or even higher. Unfortunately, there′s no effective means about the prevention and treatment for RIHD currently. Therefore, early detection and treatment about RIHD is very essential for improving curative effect and quality of life of the patients. This review discussed the diagnosis, prevention and treatment methods for RIHD.

     

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