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食管癌是我国常见的恶性肿瘤,其发病率居全世界恶性肿瘤发病率的第8位,病死率居全世界恶性肿瘤病死率的第6位[1]。我国属于食管癌高发区,且以鳞癌为主,发病率居恶性肿瘤第5位,病死率居恶性肿瘤第4位。由于早期食管癌症状不明显,发现时往往已处于晚期,在消化道肿瘤中预后最差,即使是可以手术的患者,5年生存率也仅为14%~45%[2-3]。术后局部复发与远处转移是其主要死因,改善食管癌患者远期生存的关键是探索食管癌的综合治疗模式,综合判断肿瘤原发灶及转移情况对综合治疗策略的选择及患者预后的改善至关重要。PET/CT已经成为食管癌患者标准诊断的重要手段之一,不仅可以探测原发病灶,还可以发现远处转移,在评估治疗反应、协助制定放疗计划等方面具有重要作用。PET/CT的正确使用和分析有助于食管癌患者的精准治疗并达到最佳疗效。
18F-FDG PET/CT在食管癌中的临床应用
The clinical application of 18F-FDG PET/CT in esophageal cancer
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摘要: 食管癌在我国具有较高的发病率和病死率,且病死率较发病率的排序靠前,表明该病在诊断及治疗方面仍存在很多问题。目前食管癌的诊断主要包括消化道造影、内镜活检、CT等。PET/CT作为一种新型检查方法,突破了传统检查的禁锢,将代谢图像和CT图像融合,在食管癌诊断、分期、疗效评价及预后判断等方面显示出了独特的应用价值。笔者将对18F-FDG PET/CT在食管癌中的最新研究进展进行综述。
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关键词:
- 食管肿瘤 /
- 正电子发射断层显像术 /
- 体层摄影术,X线计算机 /
- 氟脱氧葡萄糖F18
Abstract: Esophageal cancer has high incidence and mortality rates in our country. The number of mortality is greater than that of incidence, thus indicating that many problems still occur in esophageal cancer diagnosis and treatment. The present diagnosis of esophageal cancer includes gastrointestinal angiography, endoscopic biopsy, and CT, among others. As a new method, PET/CT breaks through the limitation of traditional inspection by combining the metabolic and CT images. This combination has a unique value in diagnosis, tumor staging, efficacy evaluation, prognosis, and other aspects of esophageal cancer. This article reviews the latest research. -
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