Objective To evaluate the effect of fine individual ¹³¹I treatment on patients with Graves disease hyperthyroidism.

Methods Retrospective analysis was carried out to evaluate the effect of fine individual ¹³¹I treatment on 265 cases of Graves disease hyperthyroidism. On the basis of thyroid size, the thyroid′s maximum radioiodine uptake, and the toxic nodular, the individual treatment correction coefficient was introduced to appropriately adjust the ¹³¹I dose. The therapeutic effect was evaluated through thyroid function tests 3 and 6 months post-treatment.

Results The clinical symptoms in the 265 patients with Graves disease hyperthyroidism significantly improved after the fine individual ¹³¹I treatment in 3 and 6 months. Out of the 265 Graves disease cases, the ¹³¹I therapy was effective for 168(63.4%) cases after 3 months of treatment, and the hypothyroidism incidence rate caused by the treatment was 66 (24.9%). The ¹³¹I therapy was effective for 216(81.5%) cases after 6 months of treatment, and the hypothyroidism incidence rate caused by the treatment was 74(27.9%).

Conclusion The fine individual ¹³¹I treatment of Graves disease hyperthyroidism indicated a good curative effect, which is noteworthy and promising in clinical treatment.