Objective To investigate the clinical significance of an IQQA-Liver three dimensional system in the evaluation of hepatic volume and hepatic venous drainage territory before live donor liver transplantation(LDLT) with a right lobe graft.

Methods The total hepatic volume and right hemihepatic volume of 92 donors were determined with IQQA semiautomatic method(IQQAV_total and IQQAV) and traditional CT manual method(CTV_total and CTV). Right portal vein territorial volume(RPVTV) of 92 donors were determined, and efficient functional hepatic volume(EFHV) were obtained by simulating hepatic section and venous reconstruction schedule. The preoperative right hemihepatic volume obtained via four methods were compared with the intraoperative volume(IOV) in LDLT and then evaluated through paired t test and correlation analysis between interclass data. P≤0.05 was considered statistically significant. The relationship of the diameter and the territorial volume of 254 hepatic vein were analyzed.

Results The correlation coefficients were 0.96 for CTV_total and IQQAV_total and 0.93 for CTV and IQQAV. The correlation coefficients were 0.82, 0.81, 0.77, and 0.81 for IQQAV, CTV, RPVTV, EFHV, and IOV, respectively. The correlation coefficient was 0.73 between the diameter and territorial volume of the hepatic vein(P≤0.01).

Conclusions The hemihepatic volume obtained through IQQA-Liver was associated with IOV. However, the diameter of the tributaries of the hepatic vein cannot completely represent homologous territorial volume. EFHV should be calculated to evaluate a patient′s status before operation is performed.