Objective To review retrospectively the multislice CT(MSCT) findings in a series of eight mesenteric Castleman diseases and determine their imaging features.

Methods The MSCT findings from eight patients with pathologically proved Castleman disease were retrospectively reviewed. The location, morphological features, size, margin, CT density, and contrast enhancement characteristics of the tumor were assessed.

Results Among the eight patients with mesenteric Castleman disease, seven had a single mass, and one had multiple masses. All lesions were well defined and had homogeneous hyperdensity on non-enhanced imaging, except for one lesion which had a calcification in its central area. All lesions showed marked enhancement, including seven homogeneously and two heterogeneously enhanced tumors. Five tumors in four patients had satellite nodules. All lesions in eight patients had enlarged vessels around or within the mass.

Conclusion MSCT is important to the diagnosis and differential diagnosis of primary mesenteric Castleman disease.