基于Deauville标准探讨18F-FDG PET/CT在霍奇金淋巴瘤复发诊断中的应用价值

Value of 18F-FDG PET/CT on diagnosis of Hodgkin lymphoma recurrence using Deauville criterion

    摘要
  • 摘要:
    目的 基于Deauville标准探讨18F-FDG PET/CT在霍奇金淋巴瘤(HL)复发诊断中的应用价值。
    方法 基于Deauville标准, 回顾性分析24例治疗结束后5~27个月, 临床可疑复发的HL患者, 对其18F-FDG PET/CT显像结果进行评分判断, 并与淋巴结活检和(或)骨髓活检病理结果进行对照分析。
    结果 病理结果证实17例复发、3例淋巴结反应性增生、1例肺癌并纵隔淋巴结转移、3例未见明确复发。18F-FDG PET/CT诊断HL复发的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为100%、50%、85%、100%和87%。
    结论 基于Deauville标准18F-FDG PET/CT在HL复发诊断中具有重要的临床应用价值。

     

    Abstract:
    Objective To investigate the diagnostic value of 18F-FDG PET/CT on Hodgkin lymphoma(HL) recurrence according to Deauville criterion.
    Methods Retrospective analysis was performed on 24 HL cases for a period of 5-27 months after treatment. These patients were clinically suspected of recurrence.
    Results of 18F-FDG PET/CT imaging according to Deauville criterion, lymph node biopsies, and(or) bone marrow biopsy pathology were analyzed and compared.
    Results Seventeen cases of recurrence were confirmed by pathologic findings. Three cases of lymph node reactive hyperplasia, 1 case of lung cancer with mediastinal lymph node metastasis, and 3 cases without recurrence were recorded. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 100%, 50%, 85%, 100%, and 87% for 18F-FDG PET/CT on HL recurrence diagnosis.
    Conclusion 18F-FDG PET/CT is of important clinical value on the diagnosis of HL recurrence according to the standard of Deauville criterion.

     

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