基于蒙特卡罗算法模拟的某型伽玛刀剂量场特性研究

Dose field characteristics study of Gamma knife based on Monte Carlo simulation

    摘要
  • 摘要:
    目的 针对我国自主生产的某型伽玛刀，建立一套快速、准确的蒙特卡罗算法模型，并利用所建立的模型对伽玛刀剂量场特性进行研究。
    方法 利用蒙特卡罗核粒子输运程序建立伽玛刀的蒙特卡罗算法模型，并用实验结果对模拟结果进行验证。
    结果 离轴比：和实验结果符合良好，随着准直器孔径的减小，顶部剂量率平台随之减小，半影区也有减小的趋势但不明显；等剂量曲线：旋转轴垂直平面上的剂量梯度最小。
    结论 （1）所建立蒙特卡罗算法模型是准确有效的；（2）在制定治疗计划时，需要考虑到肿瘤和体表距离、肿瘤大小、形状以及射野不均匀性带来的影响。

     

    Abstract:
    Objective To build a Monte Carlo model of a type of gamma knife independently produced in China, and prove the accuracy of this model and study dose field characteristics of the gamma knife.
    Methods Monte Carlo model was built based on Monte Carlo N-Particle Transport Code, and the simulation result was verified by the experiment results.
    Results Off Axis Ratio:the simulation result of Off Axis Ratios was in good agreement with the experiment results, the top dose rate platform decreased with the radium of the collimators reduced, penumbra decreased to some degree but not obviously; isodose curves:the dose gradient of the plane perpendicular to rotate axis was minimum.
    Conclusions (1) The Monte Carlo model was accurate and effective. (2)The distance between the tumor and body surface, the size, shape of the tumor and the heterogeneity of exposure field need to be considered when the treatment plan is developed.

     

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